The 24-year-old Byron from Charlotte, North Carolina, led a race-high 212 of 403 and fended off Joey Logano during an overtime shootout to repeat as a Cup winner at the Paperclip-shaped short track.
The 2020 NASCAR Xfinity Series champion commenced his first full-time campaign in the Cup Series by becoming the 41st different winner of the Great American Race.
The Elk Grove, California, native benefitted from a late run-in involving teammate Elliott and Harvick to win for the sixth time in 2021 at Thunder Valley.
The 2017 Cup champion rallied from an opening lap penalty to lead the final 51 laps and beat teammate Denny Hamlin to win at Richmond and advance to the Playoff's Round of 12.