The 30-year-old Chastain from Alva, Florida, led a race-high 99 of 300-scheduled laps, including the final 34, en route to his first Cup victory of 2023 in Music City.
Kyle Busch won Stage 2 at Sonoma but couldn't catch Martin Truex Jr. late and settled for the runner-up spot.
"I thought I could catch Martin," Busch said. "I gave it my best shot. There's nothing like a charge in 'Wine Country,' except for maybe a 'charge' in 'Tequila Country.'"
The 29-year-old Blaney from High Point, North Carolina, led a race-high 163 of 400 laps and withstood trials and challenges from Mother Nature to the on-track chaos to snap a 59-race winless drought in NASCAR's longest event on the schedule.
The three-time Daytona 500 champion from Chesterfield, Virginia, led 34 of 267-scheduled laps and executed a thrilling last-lap victory over Kyle Larson to notch his first Cup victory of the 2023 season.
The 2017 Cup Series champion from Mayetta, New Jersey, led 68 of 400-scheduled laps and prevailed in a seven-lap shootout to win his first Cup points-paying event since September 2021.
Kyle Larson charged early at Martinsville, and was into the top 10 by lap 20 after starting 19th. Larson surged again in the latter part of the race, holding off Joey Logano while leading.
Christopher Bell led 100 laps and held off Tyler Reddick to win the Food City Dirt Race at Bristol. Tyler Reddick attempted to catch Bell, but ran out of time and had to settle for second.
The 2021 Cup Series champion from Elk Grove, California, led 93 of 400-scheduled laps and prevailed during a late pit stop and two late-race restarts to notch his first Cup victory of the 2023 season.